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CAS 13311-84-7 Paclitaxel For Breast Cancer Treatment Natural Plant Extracts

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CAS 13311-84-7 Paclitaxel For Breast Cancer Treatment Natural Plant Extracts

Brand Name : Jusheng Brand
Model Number : 33069-62-4
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T, Western Union, MoneyGram, L/C, Bitcion, Paypal
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 13311-84-7
Apparence : Almost White Crystalline Powder
Purity : 99%
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Medicine Raw Material Paclitaxel For Cancer Treatment Drug Natural Plant Extracts


Quick detail


Product NamePaclitaxel
CAS33069-62-4
Package5g/10g
Shelf life2 years
StandardUSP34
ITEMSSPECIFICATIONSRESULTS
ASSAY (calculated on the anhydrous, solvent-free basis)97.0%~102.0%99.7%
SPECIFIC ROTATION-49.0°~-55.0°-51.4°
IDENTIFICATIONIR Infrared Absorption:In accordance with the reference Standard spectrum of paclitaxelConforms
Baccatin IIINMT 0.2%0.08%
10-Deacetylbaccatin IIINMT 0.1%Undetected
PhotodegradantNMT 0.1%Undetected
10,13-BissidechainpaclitaxelNMT 0.5%Undetected
7-AcetylpaclitaxelNMT 0.6%Undetected
7-Tes-paclitaxelNMT 0.3%Undetected
13-Tes-baccatin IIINMT 0.1%Undetected
7-EpipaclitaxelNMT 0.4%0.09%
2-Debenzoylpaclitaxel-2-pentenoateNMT 0.7%Undetected
10-Deacetyl-7-cpipaclitaxelNMT 0.4%0.03%
OthersNMT 0.1% (each)0.04%
TotalNMT 2.0%0.28%
AcetoneNMT 5000ppm33 ppm
n-heptaneNMT 5000ppmConforms
DichloromethaneNMT 600ppmConforms
WATERNMT 4.0%0.50%
RESIDUE ON IGNITIONNMT 0.2%0.06%
HEAVY METALSNMT 0.002%Conforms
BACTERIAL ENDOTOXINSNMT 0.4 EU/mgConforms
MICROBIAL LIMITSTotal aerobic microbial count NMT100 cfu/g1 cfu/g
Salmonella speciesIt meets the requirements of the tests for the absence of Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella species, and Escherichia coliUndetected
CONCLUSIONThe product is in accordance withUSP34 to test the above-mentioned items,conform to the specification
ConclusionQualified

Paclitaxel ​Description:


1Paclitaxel is a cancer medication that interferes with the growth and spread of cancer cells in the body.
2
Paclitaxel is used to treat breast cancer, ovarian cancer, and lung cancer. It is also used to treat AIDS-related Kaposi's sarcoma.
3
Paclitaxel may also be used for purposes not listed in this medication guide.
4Paclitaxel can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.


How you have paclitaxel


You usually have paclitaxel as an injection into a vein. It can cause an allergic reaction. To try to prevent this, you have a steroid injection and tablets before the paclitaxel drip. You also have anantihistamine (such as chlorphenamine) into a vein about an hour before your treatment. You will also have a medicine to prevent heartburn, such as ranitidine or cimetidine. Abraxane does not usually cause an allergic reaction so you don't need the anti allergy drugs with abraxane.


You can have paclitaxel through a thin, short tube (a cannula) put into a vein in your arm each time you have treatment. Or you may have it through a central line, a portacath or a PICC line. These are long, plastic tubes that give the drugs directly into a large vein in your chest. You have the tube put in just before your course of treatment starts and it stays in place as long as you need it.


You usually have chemotherapy as a course of several cycles of treatment. The treatment plan for paclitaxel depends on which cancer you have. You can find out about how doctors plan chemotherapy in the chemotherapy section.


Paclitaxel side effects are listed below. You can use the underlined links to find out more about each side effect. Where there is no link, use the search box at the top of the page or go to our cancer drugs side effects section.


Occasional side effects


  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • flushing (warmth, redness, or tingly feeling);
  • slow heart rate, feeling like you might pass out;
  • seizure (convulsions);
  • chest pain, dry cough, wheezing, feeling short of breath;
  • numbness, tingling, or burning pain in your hands or feet;
  • jaundice (yellowing of the skin or eyes); or
  • severe redness or swelling, severe irritation, a hard lump, or skin changes where the injection was given.

Common side effects may include:


  • mild nausea, vomiting, diarrhea, constipation;
  • weakness;
  • joint or muscle pain;
  • darkening of your skin or nails; or
  • temporary hair loss.

Important points to remember


You should not receive this medication if you are allergic to paclitaxel, or to other medications that contain an ingredient called Cremophor EL (polyoxyethylated castor oil). This includes cyclosporine and teniposide.

To make sure paclitaxel is safe for you, tell your doctor if you have:

  • HIV, AIDS, or Kaposi's sarcoma;
  • heart disease;
  • high blood pressure; or
  • liver disease.
  • Do not receive paclitaxel if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether paclitaxel passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using paclitaxel.


Paclitaxel Dosage


Paclitaxel is injected into a vein through an IV. A healthcare provider will give you this injection. You may be given other medications to prevent an allergic reaction while you are receiving paclitaxel.

Paclitaxel is usually given once every 3 weeks. Follow your doctor's dosing instructions very carefully.

Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving paclitaxel.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when paclitaxel is injected.


Paclitaxel can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.


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