Faslodex Breast Cancer Non Estrogenic Steroids Fulvestrant CAS
|Product Name||Fulvestrant , Faslodex|
|Product Categories||Intermediates & Fine Chemicals;Pharmaceuticals;Nuclear
Receptors;Chiral Reagents;Steroids;Sulfur &
|Any Individual impurity||Not more than 0.10%||0.18%|
|Total impurities||Not more than 1.0%||0.44%|
|Ratio of isomers||50.0%-60.0%||51.70%|
Fulvestrant is used to treat breast cancer that has spread to other
areas of the body in women who have gone through "the change of
life" (menopause). It is used in patients who have not responded
well to other medications (e.g., tamoxifen). Breast cancer cells
need the hormone estrogen in order to grow. Fulvestrant works by
blocking the effect of estrogen, slowing tumor cell growth.
Fulvestrant is used for treating certain types of advanced breast
cancer in women after menopause who have not responded well to
other medicines (eg, antiestrogen drugs) or therapy. It may also be
used for other conditions as determined by your doctor.
Fulvestrant is an estrogen receptor antagonist. It works by
blocking estrogen from tumors that need estrogen to grow.
Do NOT use fulvestrant if:
- you are allergic to any ingredient in fulvestrant
Contact your doctor or health care provider right away if any of
these apply to you.
Before using fulvestrant:
Some medical conditions may interact with fulvestrant. Tell your
doctor or pharmacist if you have any medical conditions, especially
if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are
- if you are able to become pregnant
- if you are taking any prescription or nonprescription medicine,
herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver or kidney problems or low blood platelet levels
(thrombocytopenia), or bleeding or clotting problems
- if you have weak bones or have had a recent broken bone, or if you
or a family member has a history of thinning of the bones
How you have fulvestrant
You have fulvestrant as two injections – one into each buttock. You
can have it at your GP surgery. Your doctor or practice nurse gives
you the injections. They each take 1 to 2 minutes. You have the
injections two weekly for the first 3 doses and then monthly
How to use fulvestrant:
Use fulvestrant as directed by your doctor. Check the label on the
medicine for exact dosing instructions.
- An extra patient leaflet is available with fulvestrant. Talk to
your pharmacist if you have questions about this information.
- Fulvestrant is usually given as an injection at your doctor's
office, hospital, or clinic. If you will be using fulvestrant at
home, a health care provider will teach you how to use it. Be sure
you understand how to use fulvestrant. Follow the procedures you
are taught when you use a dose. Contact your health care provider
if you have any questions.
- Do not use fulvestrant if it contains particles, is cloudy or
discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the
reach of children and away from pets. Do not reuse needles,
syringes, or other materials. Ask your health care provider how to
dispose of these materials after use. Follow all local rules for
- If you miss a dose of fulvestrant, contact your doctor right away.
Ask your health care provider any questions you may have about how
to use fulvestrant.